Mass Spectrometry

Fragmentation - Ethers


The molecular ion peak is usually weak, however, larger than for alcohols.

An important fragmentation process for alcohols involves the cleavage of the C-C bond to the a-carbon as shown in figure 28.

Figure 28. Cleavage of the C-C bond to the a-carbon.

Cleavage of the C-C bond to the <FONT FACE=symbol>a</FONT>-carbon.

A second common mode of fragmentation involves cleavage of the C-O bond (see figure 29).

Figure 29. Cleavage of the C-O bond of an ether.

Cleavage of the C-O bond of an ether.

Hydride transfer from a b-carbon is an important rearrangement process in ethers as shown in figure 30.

Figure 30. Rearrangement of an ether.

Rearrangement of an ether.

Peaks usually occur in CnH2nOH+ increments for ethers.

The complete mass spectrum for n-butyl ether is given in figure 31, which illustrates most of these points.

Figure 31. Mass spectrum for n-butyl ether.

Mass spectrum for n-butyl ether.


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