NMR Spectroscopy

Fluorine Coupling to 1H and 13C


Fluorine Coupling to 1H

Coupling between hydrogen and fluorine (spin 1/2) is very strong. Typical 2J coupling constants are about 48 Hz. Longer range coupling is smaller. Typical 4J coupling constants are about 4 Hz.

The figure below contains the NMR spectrum for  fluoroacetone. The nuclear spin of fluorine is 1/2. This means that the proton signal is split into n + 1 parts.

Figure. NMR spectrum of fluoroacetone.

 

Fluorine Coupling to 13C

Coupling between carbon and fluorine (spin 1/2) is very strong. Typical 1J coupling constants are about 185 Hz. Longer range coupling is smaller. Typical 2J coupling constants are about 20 Hz.

The figure below contains the NMR spectrum for  fluoroacetone. The nuclear spin of fluorine is 1/2. This means that the carbon signals are split into n + 1 parts.

Figure. NMR spectrum of fluoroacetone.

 


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