Anilide Formation



Acid Anhydride

Anilide formation for anhydride.

Acyl Halide

Anilide formation for acyl halide.


Procedure

In a small flask, place 0.2 mL of aniline, 1 mL of water, and 0.2 mL or 0.2 g of the unknown. To this solution add in portions, with vigorous shaking, 10 mL of 20% sodium hydroxide solution. Shake the solution in a stoppered flask for several minutes, and then test the solution with litmus paper to make sure that it is still alkaline.

Positive Test

Formation of a solid is a positive test.

Anhydrides and acyl halides produce anilides which precipitate.

Complications

Moisture present in the unknown will give a negative test.