Zinc and Ammonium Chloride Reduction



Nitro Compounds

Zinc and ammonium chloride reduction for nitro compounds.


Procedure

Dissolve 0.2 mL or 0.2 g of the unknown in 4 mL of 50% ethanol, and add 0.2 g of ammonium chloride and 0.2 g of zinc dust. Shake, and heat to boiling. Allow to stand for 5 min, filter, and test the action of the filtrate on Tollens reagent.

Positive Test

A positive test is the formation of a black or grey precipitate or a silver mirror.

Complications

This test depends on the reduction of the unknown to a hydrazine, a hydroxylmine, or an aminophenol; all these compounds are oxidized by Tollens reagent. This test cannot be applied if the original compound reduces Tollens reagent. Tertiary aliphatic compounds and aromatic nitro compounds give a positive test. Nitroso, azoxy, and azo compounds are reduced with zinc and ammonium chloride, with the products being oxidized in the Tollens test.